| # | Building | Images | Height | Floors | Building type | Year | Status |
|---|---|---|---|---|---|---|---|
| 1 | Holy Family Church | 2 | 226 ft | - | church | 1874 | |
| 2 | Medical District City Apartments Expansion Tower | 210 ft | 19 | high-rise building | - | ||
| 3 | Medical District City Apartments South | 1 | ≈140 ft | 12 | high-rise building | 1972 | |
| 4 | Medical District City Apartments North | 1 | ≈140 ft | 12 | high-rise building | 1972 | |
| 5 | Joan and Paul Rubschlager Building | ≈116 ft | 10 | low-rise building | 2022 | ||
| 6 | Circle Park Apartments | ≈93 ft | 8 | low-rise building | 1980 | ||
| 7 | Little Italy Branch, Chicago Public Library | ≈82 ft | 7 | low-rise building | 2019 | ||
| 8 | Columbus on the Park | ≈82 ft | 7 | low-rise building | 1910 | ||
| 9 | 1347 Fillmore Street | ≈47 ft | 4 | low-rise building | 2005 | ||
| 10 | National Italian American Sports Hall of Fame | ≈47 ft | 4 | low-rise building | - | ||
| 11 | Notre Dame Church | 5 | - | church | 1892 | ||
| 12 | St. Basil Greek Orthodox Church | 2 | - | church | 1910 |