| # | Building | Images | Height | Floors | Building type | Year | Status |
|---|---|---|---|---|---|---|---|
| 1 | WICU-TV transmitter | 700 ft | - | mast (wired) | - | ||
| 2 | St. Peter Cathedral | 265 ft | - | church | 1893 | ||
| 3 | Transmission Tower | 226 ft | - | mast (framework) | - | ||
| 4 | Renaissance Centre | 3 | 198 ft | 14 | high-rise building | 1926 | |
| 5 | Bicentennial Tower | 1 | 187 ft | - | observation tower | 1995 | |
| 6 | Transmission Tower | 180 ft | - | mast (framework) | - | ||
| 7 | Transmission Tower | 180 ft | - | mast (framework) | - | ||
| 8 | Haysite Tower | 1 | 163 ft | 13 | high-rise building | 1965 | |
| 9 | Methodist Towers | 160 ft | 13 | high-rise building | 1972 | ||
| 10 | Saint Vincent Health Center - North Building | 158 ft | 9 | high-rise building | - | ||
| 11 | Highpoint Towers | 148 ft | 15 | high-rise building | 1976 | ||
| 12 | Mid City Towers | 2 | 134 ft | 14 | high-rise building | 1976 | |
| 13 | Richford Arms | 1 | 128 ft | 10 | high-rise building | 1928 | |
| 14 | Transmission Tower | 120 ft | - | mast (pole) | - | ||
| 15 | Verizon Building | 119 ft | 7 | high-rise building | - | ||
| 16 | Boston Store Place | 1 | 116 ft | 6 | high-rise building | 1930 | |
| 17 | 901 State Street | 93 ft | 7 | low-rise building | - | ||
| 18 | Warner Theatre | 70 ft | - | low-rise building | 1931 | ||
| 19 | Erie Land Light | 49 ft | - | lighthouse | 1866 | ||
| 20 | Palace Centre | 1 | 13 | high-rise building | 1914 |