| # | Building | Images | Height | Floors | Building type | Year | Status |
|---|---|---|---|---|---|---|---|
| 1 | Heyseltoren | 1,509 ft | - | observation tower | - | ||
| 2 | Tour des Finances | 39 | 476 ft | 36 | skyscraper | 1982 | |
| 3 | Up-site | 7 | 466 ft | 42 | skyscraper | 2014 | |
| 4 | World Trade Center Tower IV | 344 ft | 28 | skyscraper | - | ||
| 5 | Palais de Justice / Justitiepaleis | 9 | 341 ft | - | monumental hall | 1883 | |
| 6 | IT Tower | 6 | 335 ft | 25 | skyscraper | 1971 | |
| 7 | The Hotel | 13 | 325 ft | 30 | high-rise building | 1967 | |
| 8 | Möbius II | 1 | 323 ft | 23 | high-rise building | 2020 | |
| 9 | Hôtel de Ville / Stadhuis | 32 | 318 ft | - | building with towers | 1454 | |
| 10 | Blue Tower | 12 | 289 ft | 25 | high-rise building | 1976 | |
| 11 | Tour Sablon | 10 | 282 ft | 27 | high-rise building | 1968 | |
| 12 | Tour Louise / Louiza Toren | 4 | 276 ft | 24 | high-rise building | 1966 | |
| 13 | TBR building | 9 | 276 ft | 22 | high-rise building | - | |
| 14 | Tour Lotto / Lotto Toren | 1 | 266 ft | 23 | high-rise building | 1962 | |
| 15 | Möbius I | 4 | 242 ft | 20 | high-rise building | 2020 | |
| 16 | MULTI | 7 | 207 ft | 19 | high-rise building | 1969 | |
| 17 | Centre Monnaie / Muntcentrum | 10 | 207 ft | 15 | high-rise building | 1971 | |
| 18 | Pacheco 44 | 6 | 184 ft | 13 | high-rise building | 1971 | |
| 19 | Berlaymont | 24 | 180 ft | 14 | high-rise building | 1969 | |
| 20 | Europa Building | 3 | 148 ft | 12 | high-rise building | 1927 |