| # | Building | Images | Height | Floors | Building type | Year | Status |
|---|---|---|---|---|---|---|---|
| 1 | U.S. Steel Tower | 18 | 256 m | 64 | skyscraper | 1970 | |
| 2 | BNY Mellon Center | 6 | 221 m | 54 | skyscraper | 1983 | |
| 3 | One PPG Place | 17 | 194 m | 40 | skyscraper | 1984 | |
| 4 | Fifth Avenue Place | 13 | 188 m | 31 | skyscraper | 1988 | |
| 5 | One Oxford Centre | 3 | 187 m | 45 | skyscraper | 1983 | |
| 6 | Gulf Building | 7 | 177 m | 44 | skyscraper | 1932 | |
| 7 | Tower at PNC Plaza | 166 m | 32 | skyscraper | 2015 | ||
| 8 | Three Mellon Center | 3 | 158 m | 41 | skyscraper | 1951 | |
| 9 | FreeMarkets Center | 2 | 156 m | 39 | skyscraper | 1968 | |
| 10 | Grant Building | 5 | 148 m | 40 | skyscraper | 1930 | |
| 11 | Koppers Building | 3 | 145 m | 34 | skyscraper | 1929 | |
| 12 | Two PNC Plaza | 2 | 136 m | 34 | skyscraper | 1975 | |
| 13 | EQT Plaza | 6 | 131 m | 32 | skyscraper | 1987 | |
| 14 | One PNC Plaza | 4 | 129 m | 30 | skyscraper | 1972 | |
| 15 | Regional Enterprise Tower | 7 | 125 m | 30 | skyscraper | 1953 | |
| 16 | First National Bank Building | 118 m | 26 | skyscraper | 1912 | ||
| 17 | Three PNC Plaza | 3 | 110 m | 23 | skyscraper | 2009 | |
| 18 | Federated Tower | 2 | 109 m | 27 | skyscraper | 1982 | |
| 19 | Westinghouse Tower | 4 | 108 m | 23 | skyscraper | 1970 | |
| 20 | Oliver Building | 1 | 106 m | 25 | skyscraper | 1910 |