| # | Building | Images | Height | Floors | Building type | Year | Status |
|---|---|---|---|---|---|---|---|
| 1 | Hochhaus am Graf-Adolf-Platz | 525 ft | 27 | skyscraper | 1921 | ||
| 2 | VICTORIA-Haus | 5 | 354 ft | 29 | skyscraper | 1998 | |
| 3 | Thyssenhaus | 6 | 311 ft | 26 | high-rise building | 1960 | |
| 4 | GAP 15 | 8 | 295 ft | 24 | high-rise building | 2005 | |
| 5 | Vodafone-Hochhaus | 7 | 290 ft | 25 | high-rise building | 1955 | |
| 6 | Johanneskirche | 286 ft | - | church | 1881 | ||
| 7 | Sky Office | 7 | 285 ft | 23 | high-rise building | 2009 | |
| 8 | Landeszentralbank | 3 | 242 ft | 26 | high-rise building | 1987 | |
| 9 | Stadtsparkasse | 3 | 236 ft | 19 | high-rise building | 1964 | |
| 10 | Stiftskirche Sankt Lambertus | 230 ft | - | church | 1394 | ||
| 11 | 25 Hours Hotel Düsseldorf | 213 ft | 19 | high-rise building | 2018 | ||
| 12 | Pandion D'Or | 200 ft | 18 | high-rise building | 2015 | ||
| 13 | Pandion Le Grand | 197 ft | 18 | high-rise building | 2017 | ||
| 14 | Eclipse | 197 ft | 16 | high-rise building | 2022 | ||
| 15 | Horizon | 197 ft | 16 | high-rise building | 2017 | ||
| 16 | Kreuzkirche | 197 ft | - | church | 1910 | ||
| 17 | Ministerium für Wirtschaft | 1 | 190 ft | 17 | high-rise building | 1967 | |
| 18 | Galeria Kaufhof Verwaltung | 190 ft | 12 | high-rise building | 1965 | ||
| 19 | Wilhelm-Marx-Haus | 3 | 187 ft | 13 | high-rise building | 1924 | |
| 20 | Herz-Jesu-Kirche Derendorf | 185 ft | - | church | 1907 |